ACTIVIN A TARGETS EXTRASYNAPTIC NMDA RECEPTORS TO AMELIORATE NEURONAL AND BEHAVIORAL DEFICITS IN A MOUSE MODEL OF HUNTINGTON DISEASE

Activin A targets extrasynaptic NMDA receptors to ameliorate neuronal and behavioral deficits in a mouse model of Huntington disease

Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD).A previous study showed Activin A, whose freetress deep twist crochet hair 14 inch transcription is upregulated by calcium influx via synaptic NMDARs, suppresses

read more


Visualisation of sentinel lymph node with indium-based near infrared emitting Quantum Dots in a murine metastatic breast cancer model.

Due to its non-invasiveness, high temporal resolution and lower cost, fluorescence imaging is an interesting alternative to the current method (blue dye and radiocolloid) of sentinel lymph node (SLN) mapping in breast cancer.Near-infrared (NIR) emitting cadmium-based Quantum Dots (QDs) could be used for this purpose; however, their wide application

read more